1991 Volume 53 Issue 3 Pages 490-497
We reported a case of a 14-year-old Japanese male presenting a nevus sebaceus accompanied by a pilomatricoma-like tumor composed mainly of shadow cells. We also reviewed 43 previous cases of nevus sebaceus treated in our clinic over the last 14 years, and confirmed the fact that the nevus sebaceus was a teratotic and nevoid disorder of pilosebaceous-apocrine units. In the proliferating epidermis corresponding to the nevus sebaceus, proliferations of trichilemmal cells derived from the underlying infundibulum of nevoid hair follicles, were observed to various extents along with proliferations of cells resembling those of tumors such as follicular infundibulum, nevus comedonicus, dilated pore of Winer, seboacanthoma and sebaceous trichofolliculoma. The above indicated that the proliferation of the epidermis in nevus sebaceus is possibly derived from proliferating trichilemmal cells in the upper part of the nevoid hair follicle.
