Abstract
We report a 30-year-old man with anaphylactoid purpura associated with nephrotic syndrome. He presented with palpable purpura on his legs, buttocks, and hands with proteinuria and hematuria. He showed nephrotic syndrome (serum protein, 5.5mg/dl; urinary protein, 5.0g/day). Biopsy specimens of the purpura lesion revealed leukocytoclastic vasculitis. In the renal biopsy specimen, cellular crescents affected 43.8% of the glomeruli, and direct immunofluorescence techniques showed granular IgA deposits within the mesangium. Our own cases with 32 patients of anaphylactoid purpura were also analyzed in regard to the incidence and prognosis of renal dysfunction.
