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Volume 61, Issue 1
Displaying 1-23 of 23 articles from this issue
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Color Atlas
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1999 Volume 61 Issue 1 Pages 1-2
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSDownload PDF (373K)
Clinical Case Reports
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Toshihiro IIDA, Chiaki NISHIYAMA, Hiroyuki IZUMI1999 Volume 61 Issue 1 Pages 3-6
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSThe patient was a four-month old boy, who was found to have facial erythema at 11 days after birth, and was brought to our department because the areas of erythema had gradually increased in size and spread over the extremeties and trunk. On presentation, mildly infiltrative areas of annular erythema the size of an adult hand were partially fused and scattered irregulary over almost his entire body. Laboratory tests were normal except for GOT and GPT levels which were occasionally raised until he was one year old. The areas of annular erythema gradually expanded and then disappeared about five weeks after his birth irrespective of his liver function. At one year of age, the patient contracted chickenpox, and the erythema totally disappeared for about 4 weeks. On the other hand, from about one year of age, areas ranging from the dorsa of the hands to the dorsal surfaces of both wrists began to show thinning of the adipose tissue resembling the symptoms normally seen in adults. Annular erythema recurred repeatedly even at 3.5 years of age.View full abstractDownload PDF (1526K) -
Tsutomu UMEKI, Saburo ANZAI, Shuji TAKASAKI, Sakuhei FUJIWARA, Susumu ...1999 Volume 61 Issue 1 Pages 7-10
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 45-year-old man was referred to us for the examination of multiple painful erythematous nodules of approximately one month’s duration on his extremities and buttocks. Physical examination revealed the characteristic appearance of thrombophlebitis migrans with erythematous nodules and post-inflammatory pigmentation in a linear arrangement on his extremities and trunk. The erythrocyte sedimentation rate and the serum level of c-reactive protein both markedly increased. An electrocardiogram showed frequent ventricular premature contractions. A biopsy specimen taken from a nodule on the forearm showed the complete luminal occulusion of medium-sized vessels with thrombi in the deep dermis, the infiltration of neutrophils and eosinophils in the vessel walls, and a slight deposition of fibrinoid material as well. Cutaneous polyarteritis nodosa was excluded due to a lack of a distinct internal elastic membrane, complete occlusion with thrombi of the blood vessels, and inconspicuous fibrinoid materials. The administration of oral corticosteroids, anticoagulants and immunosuppressants resulted in gradual improvement of the skin lesions.View full abstractDownload PDF (1328K) -
Tsutomu OKABE, Susumu SHINODA, Satoru YAMADA, Shoso YAMAMOTO, Soichiro ...1999 Volume 61 Issue 1 Pages 11-14
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 24-year-old man was admitted to our department because of purpura on his extrimities, arthralgia and severe abdominal pain. Ultrasonography of the intestine revealed wide and severe inflammatory lesions on the jejunum. A histopathological examination of the skin lesions demonstrated leukocytoclastic vasculitis. He has no abnormality in the platelets or the intrinsic (PTT) and extrinsic (PT) pathways of coagulation, but the level of factor XIII activity in his serum was far below the normal range. The administration of omeprazole (20mg/day) and predonisolone (60mg/day) did not improve the symptoms. However, the abdominal pain promptly disappeared and the intestinal lesions improved after receiving factor XIII concentrate at a dose of 1200 U for 3 days. The administration of factor XIII concentrate has been mainly used for childhood cases of Schönlein-Henoch purpura with gastrointestinal symptoms, but our case suggests that it also appears to be effective in adult, cases especially in those with severe and steroid-resistant abdominal complications.View full abstractDownload PDF (1895K) -
Maiko YOKOYAMA, Tatsurou TANAKA, Yutaka NARISAWA, Yoshiyuki TOMIYOSHI, ...1999 Volume 61 Issue 1 Pages 15-19
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSWe report a 30-year-old man with anaphylactoid purpura associated with nephrotic syndrome. He presented with palpable purpura on his legs, buttocks, and hands with proteinuria and hematuria. He showed nephrotic syndrome (serum protein, 5.5mg/dl; urinary protein, 5.0g/day). Biopsy specimens of the purpura lesion revealed leukocytoclastic vasculitis. In the renal biopsy specimen, cellular crescents affected 43.8% of the glomeruli, and direct immunofluorescence techniques showed granular IgA deposits within the mesangium. Our own cases with 32 patients of anaphylactoid purpura were also analyzed in regard to the incidence and prognosis of renal dysfunction.View full abstractDownload PDF (1741K) -
Tomoki OKUDA, Takuya TAKEMURA, Tsunao OH-I, Michiyuki KOGA1999 Volume 61 Issue 1 Pages 20-23
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 49-year-old men noted depigmented macules on the back of his hand around December 1993 which thereafter gradually spread to the head and trunk without any other symptoms. The diagnosis was vitiligo vulgaris (type A) non-dermatomal distribution. The administration of weak topical steroids was used during the follow-up period. Thereafter, an infiltrative, keratotic, and atrophic lesion occurred on his abdomen in July 1994. The lesion measuring 52mm×31mm, with well-defined margins and a lilac ring around it. Histopathologically, hyperplasia and the proliferation of collagen fibers were noted in all layers of the dermis and cellular infiltration, predominantly by lymphocytes, was also observed around the blood vessels and appendages, thus resulting in a diagnosis of morphea. The combination of vitiligo vulgaris and localized scleroderma is rare and immune disorders are said to be involved in the occurrence of both diseases, although the mechanism remains to be elucidated. However, a previous study of complicated cases revealed that type A vitiligo vulgaris to be associated with localized scleroderma in most cases.View full abstractDownload PDF (951K) -
Atushi KAGUCHI, Yuji INOUE, Tomomichi ONO1999 Volume 61 Issue 1 Pages 24-26
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 36-year-old Japanese male patient suffered burns (Grade I; 13%, Grade II; 9%) on his face, chest and back when using his private watercraft. The engine suddenly stopped, he suspected the cause might be due to the wet condition of a spark in the engine, igniting a gaslighter to dry up the head of a spark. The gasoline mixed with the air and exploded in the engine chamber. We thought this accident was due to a lack of knowledge by the patient about water craft and the close up structure of the engine chamber in the bottom of a personal watercraft.View full abstractDownload PDF (831K) -
Nobuko TAMURA, Hidefumi WADA, Megumi MIYAZAWA, Yuko YAMAKAWA, Shinobu ...1999 Volume 61 Issue 1 Pages 27-31
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSTwo cases of aquired segmental anhidrosis are reported. Case one was a 35-year-old man, who had noticed a decreased sweat secretion on the left side of his body during exercise for about a year. On inspection, he had Adie’s syndrome (tonic pupil and a disappearence of the deep tendon reflexes), and decreased and/or no perspiration over his entire body except for the right Th9-12 area. His physical status and the results of blood tests showed him to have neither endocrine, central and peripheral nervous system disorders, nor any cutaneous diseases. A skin biopsy from the non-sweating area revealed no pathological change. He was diagnosed as having Ross’ syndrome and was treated with PSL pulse therapy with little effect. Case two was a 19-year-old man, who had noticed anhidrosis on the left side of his face and chest during exercise for about 6 months without clinical symptoms. On examination, he showed no sweating on his left C1-Th3 area. He had neither endocrinological, somatic neurological, cutaneous deficits nor autonomic failure except for anhidrosis. A biopsy specimen from the non-sweating area showed no pathological change. We diagnosed him to have idiopathic segmental anhidrosis (ISA) and he was followed up with no treatment.View full abstractDownload PDF (2835K) -
Its Relation to TrichofolliculomaFumihiko ITO, Akemi ISHIDA-YAMAMOTO, Yoshio HASHIMOTO, Hajime IIZUKA, ...1999 Volume 61 Issue 1 Pages 32-36
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSTwo cases of trichogenic trichoblastoma (TGTB) are reported. A 40-year-old man (case 1) and 46-year-old woman (case 2) both presented with a dome-shaped nodule on his (or her) nose. In both cases, a well-demarcated fibroepithelial tumor with marked fibrous stromal component was histologically noted. The tumors showed a proliferation of thin epithelial strands composed of a few layers of basaloid cells and hair papilla-like structures with the formation of hairs. In case 1, a histological examination showed a connection of the tumor island to the overlying epidermis by a thin epithelial strand. In the case 1, the tumor was considered to be a multicentric type of TGTB according to the classification of Kimura. In case 2, the tumor was located in the dermis without any connection to the epidermis and it was diagnosed to be monocentric type of TGTB. In both cases a relationship between TGTB and TF was documented.View full abstractDownload PDF (3189K) -
Shoji WAKASUGI, Masayoshi JOHNO, Tomomichi ONO, Munashi OISHI, Michio ...1999 Volume 61 Issue 1 Pages 37-42
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSThe extension of pre-existing solar keratosis into squamous cell carcinoma in a case of ATLL after combination chemotherapy was started is herein reported. This case had started as a smouldering type ATLL at age 59 and thereafter developed into lymphoma 4 years later. The smouldering type ATLL started as a generalization of chronic eczema starting in the extremities, and the diagnosis was made based on the pathological and molecular biological data. The cutaneous lesions continued to worsen with some improvements by the intermittent systematic and topical use of corticosteroids. The smouldering ATLL persisted; 4 years later systemic lymphadenopathy developed. Chemotherapy was immediately given under a pathological diagnosis of a progression to lymphoma. The erythema in the left cheek suddenly elevated and became tumorous after three courses of CHOP therapy and a diagnosis of squamous cell carcinoma was made. Six months earlier, solar keratosis had been diagnosed on the face. After the diagnosis of squamous cell carcinoma, two lesions of solar keratosis were found on his face and all lesions of solar keratosis and squamous cell carcinoma were positive for p53 protein. Cellular immunity was considered to decrease both under the influence of ATLL and chemotherapy which thus contributed to the sudden appearance and extension of solar keratosis and squamous cell carcinoma. Based on these findings, it is therefore not only important to evaluate such ATLL lesions and its clinical type but also to identify any underlying infections, intraepidermal carcinoma and cellular immunity when chemotherapy is started.View full abstractDownload PDF (3301K) -
Shoji WAKASUGI, Masayoshi JOHNO, Kiyofumi EGAWA, Tomomichi ONO, Munash ...1999 Volume 61 Issue 1 Pages 43-47
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSWe report a case of adult T-cell leukemia/lymphoma (ATLL) in which the final diagnosis was made based on the findings of a molecular biological analysis. A considerable number of mites from pruritic and slightly scaly but uncrusted papules were observed over the trunk of the patient, together with systemic lymphadenopathy and lesions of molluscum contagiosum and tinea corporis over the entire skin. Histopathologically, many scabies were found in the horny layer, the intraepidermal and dermal infiltration of medium-sized atypical lymphocytes was also seen around the scabies. An immunohistochemical analysis of the papules and lymph nodes revealed dominant infiltrates of CD4 (+), CD8 (-) cells, thus indicating a helper/inducer phenotype, and a faint proliferation activity of ATLL cells due to a small amount of CD25 (+), Ki-67 (+) cells. A Southern blotting analysis using the whole probe of human T-lymphotropic virus type 1 (HTLV-1), however, showed the monoclonal integration of HTLV-1 in the papules and lymph nodes. A diagnosis of smoldering ATLL with concomitant intermediate type scabies, clinically located between the usual and Norwegian types was thus finally made. The presence of an intermediate type between Nowegian and usual scabies may possibly explain the interesting clinical aspert of ATLL.View full abstractDownload PDF (2989K) -
—Multiple Bowen’s Disease, Carcinoma of the Larynx and Thyroid Carcinoma—Hironori MATSUSHIMA, Yasuo SAKAI, Atsushi HATAMOCHI, Hirotoshi NAGAYAM ...1999 Volume 61 Issue 1 Pages 48-51
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSWe report a case of triple cancer (multiple Bowen’s disease, carcinoma of the larynx and thyroid carcinoma). A 82-year-old male noticed numerous erythematous plaques on his right Achilles’ region, as well as on both the instep and both dorsal surfaces of his fingers about two years before visiting our hospital. In addition, he was also suffered from an ulcerated nodule on his left calf for four months. On histopathological examination, the specimen from erythematous plaque revealed the epidermis to be composed of atypical, deranged keratinocytes, some of which were multinucleated. A specimen from the nodule revealed tumor nests composed of atypical cells with clear cytoplasm, individual cell keratinization and mitosis. The erythematous plaque was diagnosed as Bowen’s disease, while the nodule was considered to be clear cell squamous cell carcinoma. Furthermore, two years earlier he had been pointed out to have carcinoma of the larynx (well differentiated squamous cell carcinoma) and thyroid carcinoma (papillary carcinoma). This case was therefore considered to demonstrate triple cancer because there was a possibility that the nodule on his left calf was due to metastasis from the carcinoma of the larynx.View full abstractDownload PDF (1989K) -
Yuko OGUSU, Taturo TANAKA, Yutaka NARISAWA, Michiko UCHIYAMA, Hajime ...1999 Volume 61 Issue 1 Pages 52-54
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 49-year-old female presented with swelling and tenderness on her right ring finger. She had undergone surgery for cervical carcinoma of the uterus 15 months previously and had been treated with radiotherapy and chemotherapy. The histopathological features of the cutaneous nodule revealed squamous cell carcinoma the same as those of primary lesions of the uterus. The skin lesion was diagnosed to be metastatic cancer from the uterus. The etiology of metastatic skin cancer was also discussed.View full abstractDownload PDF (1075K) -
Relationship between Acquired Fibrokertatoma and Reactive Nodular HyperplasiaSawako AIURA, Noriyuki MISAGO, Takuya INOUE, Yutaka NARISAWA1999 Volume 61 Issue 1 Pages 55-58
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 61-year-old man presented with a finger-shaped protrusion on his right palm. The protrusion was excised, and the histopathological findings of the lesion were consitent with those of acquired fibrokeratoma (AF). Another type of acquired benign fibrous tumor is also known to accure on the palm, called as reactive nodular hyperplasia of the hands and oral mucosa (RNH). We discussed the relationship between AF and RNH based on a review of the literature, and thus concluded that RNF should be included in the entity of AF.View full abstractDownload PDF (1782K) -
Makiko IGUCHI, Takahiko TSUNODA, Kenichi ISHIZAWA, Fumiaki YUDA, Kyoko ...1999 Volume 61 Issue 1 Pages 59-61
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 76-year-old male was referred to us with a half month history of an asymptomatic erythematous lesion on his trunk. An increased percentage of monocytes (26%), promonocytes (10%), and monoblast (7%) were seen in a peripheral blood smear. Atypical cells were positive for CD 68 and lysozyme. Biopsy specimens showed the presence of a grenz zone consisting of normal connective tissue separating the normal epidermis from a diffuse infiltrate of atypical mononuclear cells in the upper half of the dermis. Atypical cells in the dermis had basophilic convoluted nuclei and eosinophilic cytoplasm. These cells were also found in the gingiva and bone marrow. The eruption disappeared after 7 days of chemotherapy for leukemia.View full abstractDownload PDF (1204K) -
Eiko WAKEYAMA, Tetsuo SHUKUWA, Ichiro KATAYAMA, Fumi TORIYAMA1999 Volume 61 Issue 1 Pages 62-66
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 58-year-old man with malignant eccrine spiradenoma which developed from a red nodule on his left arm is reported. He first noted linear multiple small nodules on his left arm 30 years ago. Six months before he noted one of these nodules to be growing rapidly. A physical examination revealed enlarged lymph nodes on left axilla. Histologically, the tumor consisted of benign eccrine spiradenoma and cystic lesions lined by atypical cells. A histological analysis also showed lymph node metastasis on the left axilla. Immunohistochemically, the tumor cells of spiradenoma and atypical cells were positive for cytokeratin and CEA. On an electronmicroscopic study, the microvilli were present on the tumor cell surface. This case was thus considered to have malignat eccrine spiradenoma which had developed from eccrine spiradenoma with axillary lymph node metastasis.View full abstractDownload PDF (2130K) -
Hisako SUWABE, Kazushi URANO, Yoshimasa KANEDA1999 Volume 61 Issue 1 Pages 67-70
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSA 53-year-old male from Atsugi City, Japan, presented with an elongating serpentine erythema on the right side of his abdomen. He had eaten Watasenia scintilloans (Hotaruika) approximately 10 days before the skin lesion developed. A laboratory examination revealed mild eosinophilia, while no serological reactions were positive to Gnathostoma or any other parasites. Considering the foodstuff which the patient had eaten, we diagnosed this lesion to be creeping disease which was probably caused by a nematode belonging to the suborder of Spirurina.View full abstractDownload PDF (1107K) -
Yoshihiro UMEBAYASHI, Michio OGASAWARA, Yoshibumi AKATSU1999 Volume 61 Issue 1 Pages 71-73
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSWe encountered two cases of Pasteurella multocida infection following cat bites. Case 1. A 56-year-old man was bitten on his hand by a pet cat. Case 2. A 41-year-old woman was scratched and bitten on her leg by a pet cat. The patients thereafter developed redness, swelling on the hand/leg and purulent discharge from the wound. Bacterial cultures of the pus isolated Pasteurella multotida. They were successfully treated by 2-week administration of cephems. It is important to recognize that cat bites often cause Pasteurella multocida infections.View full abstractDownload PDF (775K)
Clinical and Investigative Report
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Keisuke HAGIWARA, Kayo SINJO, Yuko HANNITA, Shigeo NONAKA1999 Volume 61 Issue 1 Pages 74-78
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSThe serum histamine and eosinophil cationic protein (ECP) levels were measured in 12 cases of physical urticaria, including patients with mechanical urticaria (n=8), cold urticaria (n=3), and solar urticaria (n=1), both before and after performing a provocation tests for each case. The same measurements with the same provocation tests were also performed two weeks after the administration of oxatomide. Both parameters showed significant differences before and after the provocation tests i. e., 0.961±0.949→2.06±2.22, p<0.005 (histamine), 15.6±9.81→26.1±21.2, p<0.01 (ECP) (Wilcoxon test, (histamine) ECP)). However, these significant differences disappeared two weeks after the administration. Eosinophils may thus play a greater role in the early stage of wheal formation in physical urticaria than had been previously thought.View full abstractDownload PDF (1333K)
Review
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[in Japanese], [in Japanese]1999 Volume 61 Issue 1 Pages 79-83
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSDownload PDF (1379K)
Therapy
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[in Japanese], [in Japanese], [in Japanese]1999 Volume 61 Issue 1 Pages 84-87
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESS -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1999 Volume 61 Issue 1 Pages 88-90
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESS
Dermatologists around the World
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[in Japanese]1999 Volume 61 Issue 1 Pages 97-98
Published: February 01, 1999
Released on J-STAGE: October 14, 2010
JOURNAL RESTRICTED ACCESSDownload PDF (1482K)
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