Three Cases of Intramuscular Granuloma

Abstract

We report three cases of intramuscular granuloma. Case 1: A 61-year-old woman developed subcutaneous tumors on her extremities and lower jaw, which gradually increased in size. Histopathologically, the tumors showed granulomatous structures composed of multinucleated giant cells and epithelioid cells in the muscle. Coupled with the laboratory findings, the patient was diagnosed to have sarcoidosis. Case 2: A 53-year-old woman developed a subcutaneous tumor on the left side of her lower jaw. Histopathologically, a granuloma composed of epithelioid cells was noted in the muscle. In addition, Actinomyces israelii was also isalated from the tissue fragments. We treated the patient with oral benzyl penicillin postassium. Case 3: A 33-year-old man developed a subcutaneous tumor on the right side of forehead. Histopathologically, the tumor showed the features of a granuloma composed of epithelioid cells and multinucleated giant cells. Some crystalline silicas were observed in the granuloma. Intramuscular granulomas have so far been sporadically reported in the orthopedic field, but seldom in the dermatological field.