Abstract
A 37-year-old woman presented with chemosis after a long period of sun exposure followed by facial edema. One month later, she visited our clinic because of fever and diarrhea. The first examination revealed severe chemosis, periorbital and facial edema, and faint erythema on her cheeks. Over the next few days, the facial edema worsened and a butterfly rash appeared. Biopsy specimen revealed basal layer degeneration and moderate perivascular inflammation. Laboratory values indicated leukopenia, thrombopenia, and hypocomplementemia. Antinuclear antibody and anti-ds DNA antibody were positive. Photosensitivity, oral ulceration, and serositis were also observed. Based on these findings, she was diagnosed as having SLE and given prednisolon 25 mg/day. After the dosage of prednisolon was increased to 50 mg/day, symptoms and abnormal laboratory findings were improved. Although human parvovirus B19 IgM antibody was positive at the first laboratory examination, results later became negative. It was considered that human parvovirus B19 infection was concomitant with SLE.
