Serum and Synovial Fluid Proteins in Patients with Arthritis

Abstract

Serum and synovial fluid were collected from 80 patients with osteoarthritis and 10 patients with rheumatoid arthritis and the protein fractions of them were estimated electrophoretically.
The following results were obtained:
1) Synovial fluid was found to contain 5 welldefined components.
2) The electrophoretic patterns of the total serum and synovial fluid proteins were almost similar in each cases.
3) Serum and synovial fluid proteins of osteoarthritis showed higher albumin, but lower gamma globulin levels than that of rheumatoid arthritis.
4) The total protein in the synovial fluid of osteoarthritis was approximately 3.05/dl in old age.