Abstract
A small series of patients with malignant bone or soft tissue tumors treated by chemotherapy with macrophage colony stimulating factor (M-CSF) or granulocyte colony stimulating factor (G-CSF) were reviewed. During the course of severe chemotherapy, bone marrow suppression was noted and G-CSF or M-CSF used for treating this. Although both G-CSF and M-CSF increased the number of peripheral granulocytes, G-CSF was more effective. Platelets and monocytes were also increased in number by G-CSF or M-CSF. Side effects were seen. in one case, however, they were minor and did not require treatment. G-CSF and M-CSF were nafe and useful.
