Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
A Case, 8-year old boy, with macroamylasemia
Katsuhiko KUBOYoshio HARADAHidemi ABIKOTadaaki IWATAKEKazuhiko KUNISHIGEHiroaki MURAKAMIKunio ARIYOSHIMitsuhiko TANABEMinoru UMEDASachiyo MISAWASyunshuke MIGITATadayoshi TAKEMOTO
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1977 Volume 74 Issue 4 Pages 479-487

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Abstract

A boy was admitted to the hospital with complaint of epigastric pain. On medication of antacid, he become well.
The diagnosis of macroamylasemia was induced by the persistence of high serum amylase level due to remarkable low amylase clearance.
The molecular size of this macroamylase was shown as approximate 7S level by means with Sephadex G150 Superfine thin layer chromatography and with concentrative procedure adding dry Sephadex G75 grain to serun.
The abnormal amylase was specifically precipitated with anti-human IgA rabbit antiserum.
This might be the first reported case of the first decade of macroamylasemia.

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© The Japanese Society of Gastroenterology
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