Abstract
Lipid and fatty acid metabolism in human is usually measured by using whole bloods or sera of subjects and by detecting lipids and fatty acids in serum or erythrocytes with biochemical and chromatographic apparatus in clinical laboratory. On the other hand, many trials have been made for a long time to develop non-invasive diagnostic methods for monitoring lipid and fatty acid metabolism in human instantly at anywhere and anytime, especially to contribute for personal health care. For this purpose vibrational spectroscopy such as FTIR used for lipid and fatty acid measurements seems promising because of its analytical advancement and mobility. The technique of NMR spectroscopy for non-destructive measurement of human serum lipoproteins has been established and contributed to various epidemiological researches. These spectroscopic techniques are suitable for non-invasive or non-destructive and instantaneous measurements, and expected for further development of clinical measurements of lipid and fatty acid metabolism in human.