Development of Porous Ultra-low-density Biomaterials by Using Precisely Controlled Spontaneous Emulsification

Abstract

The spontaneous emulsification is the phenomenon that droplet formation is achieved by contacting two immiscible solutions that are not in equilibrium. The author has reported the facile technique to prepare surface-modified polymeric nano/microparticles by an evaporation of organic solvents from o/w emulsion containing hydrophobic polymers and polymeric surfactant. In the research process, the author found that porous ultra-low-density particles were successfully obtained by using precisely controlled spontaneous emulsification. The review provides a brief review on recent efforts to develop the porous ultra-low-density biomaterials and their perspective.