Chrono-nutrition Studies on Metabolic Diseases

Abstract

The quality and quantity of nutrition are well-accepted determinants of health. On the other hand, endogenous circadian clock governs daily nutritional rhythms such as nutrient digestion, absorption, and metabolism, which are coordinated by behavioral rhythms such as activity-rest and feeding-fasting cycles. Therefore, circadian rhythm disruption causes various physiological impairments such as sleep disorders and metabolic diseases. Chrono-nutrition is the research field that studies the time-of-day effect of food intake on health and that develops the functional food that improves circadian rhythms of physical performance. In the present review, I have tried to summarize the recent studies on the effectiveness of time-restricted feeding on the prevention and improvement of metabolic diseases, such as diabetes and obesity.