Abstract
With the aim of developing new drugs, new technologies such as genomic research, combinatory chemistry and so on are useful for the screening and synthesizing of new compounds. The tendency of the new compounds shows sparingly water-soluble character. So it is necessary to use new device or high technology for the formulation using such compounds.
The technology of lipids sphere is used for the improvement of bioavailability, for controlled release and targeting of moderately water-soluble drugs. However, lipids sphere has many problems such as physical stability, amounts of enclosed drug, handling and so on.
In this paper, we explain the properties of lipid spheres, and our new studies about (1) stability of nano-emulsion in heating process, (2) controlled release from nano-emulsion, (3) lording capacity of drug in nano-emulsion.
