Abstract
The deacyled phosholipid : Glycerophosphocholine (GPC), is a water-soluble compound which was found to deacylated two fatty acids from a phosphatidylcholine (PC), a kind of phospholipid. GPC or α-GPC is used in the preparation of medical supplies and functional foods as an agent which provides choline. The FDA in America has approved nutrient containing foods and dietary supplements such as choline. GPC is produced by the digestion of PC and is a absorbed by lymph vessels. The compound is partially eliminated by the portal vein. GPC is present in organisms, thus showing it to be safe and without any toxic effect. The compound is taken up by the central nervous system following peripheral administration and functions as an acetylcholine precursor to help restore memory capacity.
GPC was examined for application to the treatment of cerebrovascular disease, reduction of senile dementia (cognitive dysfunction), improvement in learning ability and promotion of non-REM sleep.
