Oleoscience
Online ISSN : 2187-3461
Print ISSN : 1345-8949
ISSN-L : 1345-8949
Reevaluation of Saturated Fat by the Comprehensive Analysis of the Function of Fatty Acid from the View of Nutrigenomics
Yoko FUJIWARA
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2008 Volume 8 Issue 10 Pages 437-446

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Abstract
Since saturated fatty acid is believed to increase blood cholesterol and the risk for cardiovascular disease (CVD), low fat and low saturated fatty acids diet has been recommended. However, we need think about the saturated fat intake again since obesity is related to lifestyle-related diseases. Moreover, high carbohydrate diet increases the plasma TG levels. Therefore, it is necessary to reassess and reevaluate the balance between the fat energy ratio and fat quality vs total energy and carbohydrates. Recent study on the effect of dietary composition analyzed using nutrigenomics showed that the effect of diet was more significant by the decrease in total body fat caused by calories restriction, than the direct effect of fatty acids from on tissue. Dietary saturated fatty acid may result in the increase of HDL cholesterol depends on individual subject and dietary composition, which is a merit other than the increase in LDL cholesterol. It implies that the quantity and quality of lipids intake should consider the amount of carbohydrate intake and individual difference.
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© 2008 Japan Oil Chemists' Society
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