Abstract
In the literature relevant knowledge is available about the properties and physiological effects of CO2 and H2S. Both gases penetrate the skin easily and increase microcirculation of the skin. Additionally, effects on thermal receptors (CO2) and pain perception (H2S) have been demonstrated in several trials. Other effects of H2S refer to a modulation of immune cells. From this knowledge indications and contraindications may be derived. However, there is a need for prospective controlled trials to prove the efficacy of such treatments. Future directions and perspectives of research using these balneological remedies will be discussed.
