1986 Volume 49 Issue 3 Pages 118-122
Sodium succinate is remained behind following artificial CO2 bathing, prepared with a 50g sodium hydrogencarbonate and succinic acid tablet producing fine bubbles in water.
2NaHCO2+(CH2)2→(COOH)2→(CH2)2(COONa)2+H2O+CO2
Na2CO3+(CH2)2(COOH)2→(CH2)2(COONa)2+H2O+CO2
Balneotherapeutic effect of sodium succinate was evaluated experimentally using 10 rabbits by means of medical mass spectrometry.
Subcutaneous PO2 and PCO2 did not change during the bathing and tissue perfusion of 21.30±3.48ml/100g/min (mean±standard error), SD=4.94, p<0.05 was evaluated at 36-37°C, demonstrating no significant difference compared with that of 20.85±3.56ml/100g/min, SD=6.71, p<0.05 by plain water bathing.
These data showed clearly that the balneotherapeutic effects of an artificial CO2 bathing prepared with a CO2-tablet, “BUB”-KAO, was not from organic salt of sodium succinate but from CO2.
