Organ Biology
Online ISSN : 2188-0204
Print ISSN : 1340-5152
ISSN-L : 1340-5152
妊婦・授乳婦における薬物療法と胎児・乳児リスクの評価
林 昌洋
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ジャーナル フリー

2011 年 18 巻 3 号 p. 279-286

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While careful consideration to avoid a second scourge like thalidomide is required, disadvantages for mothers and fetuses by restraint of necessary drug prescription because of too much concern about the effects on fetuses must be avoided. Information sources to evaluate teratogenicity of drugs themselves include epidemiological investigations, case reports, and animal reproduction studies and are considered more reliable in this order. And breast milk is the best source of nutrition and it also serves as a source of substances providing immunity for a newborn infant. However, there are times when nursing mothers may have to take some kind of medication, so it is necessary to evaluate the effect of drugs that are transferred to infants through breast milk, and to select medications with minimal adverse effects.
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© 2011 日本臓器保存生物医学会
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