Abstract
It is no doubt that a new methodology to repair grafts from extended criteria donor(ECD)is necessary in a clinical settings of organ transplantation. The superiority of organ perfusion, to cold storage, is generally accepted in ECD grafts. However, it is still difficult to resuscitate grafts by oxygenated perfusion regardless of perfusion temperature when the grafts were subjected to warm ischemic insult and subsequent cold storage. Therefore, to establish a reliable method to resuscitate DCD grafts by oxygenated perfusion, reduction of cold preservation injury is one of the important issues as well as seeking for the optimal conditions of perfusion. We reviewed the efficacy and roles of simple cold storage and organ perfusion from the viewpoints of clinical use, with special reference to DCD grafts.
