過去10年間に当科で陽子線治療を行った頭頸部癌に関する検討

大久保 英樹; 中山 雅博; 廣瀬 由紀; 田中 秀峰; 西村 文吾; 星野 朝文; 上前泊 功; 飛田 忠道; 辻 茂希; 田渕 経司; 和田 哲郎; 原 晃; 橋井 晴子; 石川 仁; 水本 斉志; 奥村 敏之; 櫻井 英幸

doi:10.11453/orltokyo.56.s118

TREATMENT OF HEAD AND NECK CANCER BY PROTON BEAM RADIOTHERAPY DURING THE LAST 10 YEARS AT TSUKUBA

Hideki Okubo, Masahiro Nakayama, Yuki Hirose, Shuho Tanaka, Bungo Nishimura, Tomofumi Hoshino, Isao Uemaetomari, Tadamichi Tobita, Shigeki Tsuji, Keiji Tabuchi, Tetsuro Wada, Akira Hara, Haruko Hashii, Hitoshi Ishikawa, Masashi Mizumoto, Toshiyuki Okumura, Hideyuki Sakurai

Author information

Hideki Okubo
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Masahiro Nakayama
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Yuki Hirose
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Shuho Tanaka
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Bungo Nishimura
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Tomofumi Hoshino
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Isao Uemaetomari
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Tadamichi Tobita
Department of Otolaryngology, Mito Red Cross Hospital
Shigeki Tsuji
Tsuji ENT Clinic
Keiji Tabuchi
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Tetsuro Wada
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Akira Hara
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Haruko Hashii
Department of Radiation Oncology, University of Tsukuba Hospital
Hitoshi Ishikawa
Proton Medical Research Center, University of Tsukuba
Masashi Mizumoto
Proton Medical Research Center, University of Tsukuba
Toshiyuki Okumura
Proton Medical Research Center, University of Tsukuba
Hideyuki Sakurai
Proton Medical Research Center, University of Tsukuba

Keywords: proton, head and neck cancer, treatment, clinical study

JOURNAL FREE ACCESS

2013 Volume 56 Issue Supplement1 Pages s118-s122

DOI https://doi.org/10.11453/orltokyo.56.s118

Details

Abstract

A total of 61 patients with head and neck cancer received proton beam radiotherapy at the University of Tsukuba hospital between January 2002 and December 2011. The patients included 22 with sinonasal cancer, 12 with nasopharyngeal carcinoma, 11 with mesopharyngeal carcinoma, and 16 with other sites.
Of the total number of tumors treated, 52 were judged as showing complete or partial response, and the overall 5-year survival rate of the patients was 70.6%; furthermore, the 5-year survival rate was 64.4% in cases of sinonasal cancer and 87.5% in cases of nasopharyngeal carcinoma. Brain necrosis was observed in 2 patients with intracranial tumor invasion.
Proton beam therapy is effective for the treatment of head and neck cancer, especially for that of nasopharyngeal and sinonasal cancer. Further study will be needed for evaluation of the safety and efficacy of proton therapy for the treatment of other types of head and neck cancer.

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