Abstract
Alevaire is a non-irritating, non-toxic, chemically stable compound composed chiefly of the detergent, Superinone, and possesses a mucolytic action. It facilitates the elimination of tenacious secretions by moistening, reducing the surface tension and liquifying the thick secretions and thus assists the ciliary action of the mucous membrane.
The authors report their clinical experience with Alevaire (Winthrop) employed in the therapy of chronic sinusitis in children. The dissolving action of Alevaire on purulent secretions discharged from the maxillary sinus was first tested in vivo before clinical application. The following two methods were employed in their clinical cases.
1. Aerosol treatment with a nebulizer in 29 cases.
2. Injection of Alevaire into the maxillary sinus in 12 cases.
According to the authors, Alevaire was observed to be considerably effective in dissolving and loosening thick, viscid secretions and hastening their elimination. As the principal efforts in the therapy of chronic sinusitis should be directed toward removal of purulent secretions and recovery of normal ciliary action, the use of Alevaire in this respect is quite rational and they envisioned the possibility of this agent being widely used in the future.
