Abstract
In 29 cases of head and neck carcinoma, radical treatment was performed using three methods consisting Futrafur Suppository (FT-5) +radiotherapy (group 1), FT-S +radiotherapy + BLM, local or intravenous injection, (group 2) and FT-S+ radiotherapy +BLM intra-arterial infusion (group 3) to determine clinical efficancy of each treatment modality. Among the cases, 27 were evaluable.
Primary effect was observed in 26 cases (96.3%) that received radical treatment. One case of group 3 showed no response and died. Local recurrence was observed in six cases (22.2%) in 3-14 months after the initial radical treatment. They were one cases of group 1. two of group 2 and three of group 3. Six cases who were two cases of group 2 and four of group 3 died of the diesease and one case died of a disease unrelated to carcinoma.
Side effect due to the treatment developed in 11 cases (37.9%) out of 29 cases but severe side effect was not encountered.
