Abstract
An 18-year-old girl complained of profound deafness in her both ears during prednisolone therapy for systemic lupus erythematosus. Audiograms demonstrated a profound sensorineural hearing loss in the left ear and a moderate hearing loss in the right ear. SISI test showed 100% in 2, 000 and 4, 000 Hz of the right ear, suggesting that sensorineural hearing loss was caused by an inner ear damage. The patient was treated with systemic and/or oral administration of prednisolone, prostaglandin, vitamin B12 and ATP. Unfortunately, however, her hearing did not become better. The authors thought that sensorineural hearing loss was caused by angitis and/or thrombosis of the labyrinthine artery during the course of systemic lupus erythematosus.
