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[in Japanese]
1993 Volume 36 Issue 5 Pages
545-553
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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AN IMMUNOHISTOCHEMICAL STUDY.
Masaya Fukami, Pontus Stierna, Nobuyoshi Ohtori, Kiyoshi Yanagi, Hiros ...
1993 Volume 36 Issue 5 Pages
554-562
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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The localization of lysozyme (LZ) and lactoferrin (LF) in the human maxillary sinus mucosa was studied immunohistochemically. Forty-nine specimens from patients with chronic sinusitis and 13 specimens from normal controls were used. LZ and LF were observed in goblet cells and serous cells of submucosal mixed glands. In the mucosa from patients with chronic sinusitis, the staining reaction to LZ appeared to intensify in goblet cells. LZ and LF were also found in newly formed atypical glands and the apical part of epithelial cells in the mucosa from patients with chronic sinusitis. In normal mixed glands, the mucous cells containing mucin and the serous cells containing LZ and LF could be distinguished. However, in goblet cells, the apical part of some epithelial cells and cells of atypical glands, LZ, LF and mucins appeared to be localized to the same cells. The results of the present study suggest that the LZ, LF and mucin secreting activity of the secretory cells vary according to functional stage of the inflammatory processes, and LZ and LF may play a part in the course of chronic sinusitis.
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Kenji Baba, [in Japanese], Minoru Matsumoto, [in Japanese], Tadayoshi ...
1993 Volume 36 Issue 5 Pages
563-571
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Recently, hyperthermia is used as a treatment of nasal allegy. We examined the effect of hyperthemia in causing histamine release from rat purified mast cells, and histamine release was assayed with a fluorescence spectrophotometer in accordance with the method described by Shore et al. Specific Ag (DNP-As), compound 48/80 and substance P were examined as secretagogue. After 60 minutes incubation at temperature range from 43°C to 45°C, all secretagogue failed to cause histamine release. And incubation at 43°C for 10 minutes to 20 minutes, histamine release was inhibited. These effects continued for 5 hours or more. On the other hand, no degranulation was observed directly after treatment at 43°C for 1 hour and no morphological difference from treated at 37°C group under an inverted phase contrast microscope. The results suggest that hyperthermia therapy have anti-allergic effect.
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Shinya Ohashi
1993 Volume 36 Issue 5 Pages
572-581
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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The 22-channel cochlear implant has been performed on 60 postlingually profoundly deafened adult patients at Tokyo Medical College Hospital. Although the patients showed a remarkable restoration in speech sound perception, most of them remain hard of hearing, and need the help of lipreading.
Consonant confusion matrices were collected for cochlear implant alone and cochlear implant plus lipreading conditions for twenty-three 22-channel cochlear implatees. Average scores of correct response for 14 Japanese consonants were 50% for the cochlear implant alone condition and 85% for the cochlear implant plus lipreading condition. Infomation transmission analysis revealed that average infomation transfer ratios were the highest for voicing and semivowels and the lowest for nasality in the cochlear implant alone condition, while under conditions of implant plus lipreading the ratio was the highest for the place of articulation and the lowest for nasality. The results showed that infomation transfer ratios were improved by 25 to 35%, when aided by lipreading. Multiple regression analysis indicated that nasality and semivowels were contributing features for consonant recognition with cochlear implant alone, and the place of articulation was most influential for consonant recognition under cenditions of chochlear implant plus lipreading.
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Yukie Kaneko, Yasutaka Kikuchi, Shiro Esaki, Kazuhiro Aoki, Hiroshi Mo ...
1993 Volume 36 Issue 5 Pages
582-590
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Otitis media with effusion (OME) is caused by inflammation of the epipharynx, eustachian tubal dysfunction and discharge into the mastoid cavity. These process is associated with the change in the middle ear mucosa. We performed histopathological study on the middle ear mucosa in OME in children, and also investigated the relation to the mastoid pneumatization and to adenoids.
The subjects consisted of 27 cases or 34 sides of OME in children aged from 4 years to 14 years. Middle ear mucosal samples were taken during adenoidectomy and insertion of middle ear ventilation tube under general anesthesia. Before tube insertion, we did myringotomy and carried out biopsy. We studied the epithelium and the subepithlial layer of the middle ear mucosa and classified them into 4 categories.
On the result, severe subepithelial layer changes were observed in 53% of the cases in poorly pneumatized mastoid cell group. On the other hand, these changes were observed in 17% of the cases in the well pneumatized mastoid cell group.
Adenoid changes were observed in 71% of cases with OME in children.
Adenoid appeared to play an important role in the etigology of OME.
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Toshimitsu Kobayashi, Masako Ishidoya, Masaru Toshima, Toshinori Sato, ...
1993 Volume 36 Issue 5 Pages
591-594
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Bismuth iodoform paraffin paste (BIPP) is a time-honoured antiseptic dressing widely used in England, however, its use is rarely reported in Japan.
In order to evaluate the effectiveness of BIPP as mastoid packing materials, mastoid cavities of 31 ears were packed with gauzes impregnated with BIPP and bacteriological study was undertaken before and after surgery.
None of the cases showed an obvious infection one week after the operation when the packing was removed, and bacteriological examinations revealed sterile or decreased bacteria in the packed cavity.
BIPP seemed to be most uneful as a packing material in an ear after open-method tympanoplasty.
This material has also been used in treating ears with cavity problems, and has shown to have effects to reduce otorrhea.
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Tadashi Ishimaru, Toru Takimoto, Koji Imoto
1993 Volume 36 Issue 5 Pages
595-600
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Bilateral sudden deafness in a 69-year-old woman with diabetes mellitus is reported. It occurred on bilateral ears at the same time. She had been suffered from diabetes mellitus for 16 years. Because her treatment was not satisfactory, her blood sugar was 404 (mg/dl) when she consulted authors at first. She also had diabetic retinopathy whose grade was Scott V. It was thought that the microangiopathy occurred in the inner ears because changes in the blood vessel of the inner ear in diabetes mellitus have a relationship to retinal one. This microangiopathy seemed to have caused sudden deafness in this case. We reviewed literature for bilateal sudden deafness caused by diabetes mellitus and other diseases.
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Makoto Hasegawa, Yuzuru Nakamura, Norihiko Ishikawa, Teruo Kayano
1993 Volume 36 Issue 5 Pages
601-606
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Two cases of adenoid cystic carcinoma of the external auditory canal have been treated at the Department of Otorhinolaryngology, Tokyo Medical and Dental University, from 1983 to 1992. The first case, a 56-year-old female, underwent total excision of the external auditory canal skin including the cartilage of the orifice, partial parotidectomy with preservation of the facial nerve and resection of the antero-inferior part of the external auditory canal bone, on May 17, 1985. This patient is now surviving without recurrence or metastasis for about 8 years. The second case, a 79-year-old female, underwent tumor resection with surrounding normal skin of the external auditory canal on January 27, 1988. This specimen was diagnosed as adenoid cystic carcinoma later, and then this patient was advised to have partial parotidectomy with preservation of the facial nerve and additional excision of the external auditory canal including skin, cartilage and bone. However, she refused to have additional surgery. This patient was carefully followed up at the outpatient clinic and showed neither recurrence nor metastasis for about 3 years. But she suddenly suffered from acute abdomen and died on February 24, 1992. The modalities of the treatment are discussed.
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Hisae Naito, Hideki Muraoka, Nobuyuki Nozaki, Atsushi Komatsuzaki
1993 Volume 36 Issue 5 Pages
607-613
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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A 27-year-old woman affected with sudden hearing loss on both ears at the same time has been reported with review of relevant literatures. She visited us complaining of bilateral hearing loss.
Through clincal and extensive examinations which contain MRI, she was diagnosed as having bilateral acoustic tumors coming from multiple schwannoma.
In order to make definitive diagnosis between multiple schwannoma and neurofibromatosis type II, her gene analysis will be planed in near future.
We regarded the disturbance of blood circulation in the inner ears as a cause of bilateral sudden hearing loss.
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Tomoki Fujiwara, Masami Masaki, Hikoyoshi Kaitou, Kazuhiko Soejima
1993 Volume 36 Issue 5 Pages
614-618
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Nerve sheath tumors occurring in the nasal cavity and the paranasal sinus are very unusual. In the Japanese literature to date, only 13 cases of neurofibroma with direct involvement of the nasal cavity and the paranasal sinus have been reported. We reported a case of neurofibroma of nasal cavitiy.
The patient was a 48-year-old female who had right-sided nasal obstruction and nasal discharge. Anterior rhinoscopy revealed a firm, pale mass, with a smooth mucosal surface and diastolic vessels, which looked like a nasal polyp, completely filling her right posterior nasal cavity. An MR study of her sinuses showed a large mass in the right ethmoid sinus, extending into the nasopharynx.
In histopathology the excision specimen composed of spindle cells and nerve fibers. The immunohistochemial study showed the presence of S-100 protein.
The treatment of benign peripheral nerve sheath tumors is total local excision. But it is difficult because neurofibroma is unencapsulated, and malignant transformation may occur by an operative damage. Therefore, in this case we have choiced partial excision and follwed with the attention to malignant transformation.
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Kouji Otsuka, Fumihisa Hiraide, Hideki Yamaguchi, Hiroyuki Fujita, Sot ...
1993 Volume 36 Issue 5 Pages
619-623
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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An 18-year-old girl complained of profound deafness in her both ears during prednisolone therapy for systemic lupus erythematosus. Audiograms demonstrated a profound sensorineural hearing loss in the left ear and a moderate hearing loss in the right ear. SISI test showed 100% in 2, 000 and 4, 000 Hz of the right ear, suggesting that sensorineural hearing loss was caused by an inner ear damage. The patient was treated with systemic and/or oral administration of prednisolone, prostaglandin, vitamin B12 and ATP. Unfortunately, however, her hearing did not become better. The authors thought that sensorineural hearing loss was caused by angitis and/or thrombosis of the labyrinthine artery during the course of systemic lupus erythematosus.
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Katsunori Ishibashi
1993 Volume 36 Issue 5 Pages
624-635
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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Odontogenic tumours and tumour-like lesions are relatively rare in oral and maxillofacial region. Most of them are benign and develop and grow slowly inside of the jaw without pain. Since the clincal course, behaviors and histopathological features of them have many points of resemblance to each other, there are considerable diagnostic difficulty both for the clinician and pathologist. And recognition and understanding about histogenesis of the tooth may be necessary for appropriate diagnosis of these lesions.
Many attempts have been made to classify the tumours and tumour-like lesion of the odontogenic tissues.
In 1992, the new classificaton of the odontogenic tumours, entitled “Histological Typing of Odontogenic Tumours”, were published by WHO. This classification is based on clinical behavior of the tumours and histologically embryonal inductive principles and elements of the odontogenic tissues in the tumours.
According to this classification, incidence, clinical behavior and histopathological characteristics of the odontogenic tumours were presented with typical clinical cases of ameloblastoma and odontoma. As to relatively rare cases of odontogenic tumour, adenomatod odontogenic tumour, calcifying odontogenic cyst and odontogenic fibroma and other several cases were presented. Also treatment of odontgenic tumour were discussed with reference to conservative surgical method.
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[in Japanese]
1993 Volume 36 Issue 5 Pages
636-642
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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[in Japanese], [in Japanese]
1993 Volume 36 Issue 5 Pages
650-656
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
1993 Volume 36 Issue 5 Pages
657-662
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
1993 Volume 36 Issue 5 Pages
663-669
Published: October 15, 1993
Released on J-STAGE: August 10, 2011
JOURNAL
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1993 Volume 36 Issue 5 Pages
e1
Published: 1993
Released on J-STAGE: August 10, 2011
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