Abstract
Studies in aerosol therapy for the larynx have suggested that at vocalization, much amount of aerosol drug is able to be deposited because path of vocal cords becomes narrow. The mechanism for this particle deposition was investigated using both a model cast and a living organ of human larynx to check partial deposition efficiency for each part of larynx. Total aerosol deposition was found to be characterized by higher efficiency of particle impaction and circulated air flow formed as the narrow path of the vocal cords. The effectiveness of SPSU-12 nebulizer with a mouth adapter was examined in relation to the clinical testings for acute and chronic laryngitis by means of evaluating the disease types and the drug availability of pathogen.
