慢性副鼻腔炎におけるニューマクロライドの有効例・無効例の検討

平野 浩二; 池田 勝久; 下村 明; 大島 猛史; 近藤 芳史; 高坂 知節

doi:10.11453/orltokyo1958.38.Supplement3_251

CLINICAL INVESTIGATION OF EFFECTIVENESS AND INEFFECTIVENESS IN PATIENTS WITH CHRONIC SINUSITIS IN THE TREATMENT OF NEWLY DEVELOPED MACROLIDES

Koji Hirano, Katsuhisa Ikeda, Akira Shimomura, [in Japanese], Yoshifumi Kondo, Tomonori Takasaka

Author information

Keywords: chronic sinusitis, macrolide, ostiomeatal unit, nasal polyp

JOURNAL FREE ACCESS

1995 Volume 38 Issue Supplement3 Pages 251-257

DOI https://doi.org/10.11453/orltokyo1958.38.Supplement3_251

Details

Abstract

Two types of newly developed 14-membered macrolides were administered to 31 patients with chronic sinusitis for 2 to 3 months. The clinical efficacy was compared with effects of macrolides on the patency of ostiomeatal unit (OM unit) revealed by CT scan and the size of nasal polyps. The final efficacy was 38.4%. Non-responder to macrolide treatment tended to show a complete obstruction of the OM unit. In patients with severe obstruction of the OM unit. The presence of large nasal polyps in the middle nasal meatus seems to be a critical factor of cause resistance to the macrolides.

Corresponding author

Register with J-STAGE for free!