Abstract
Rendu-Osler-Weber disease (Hereditary Haemorrhagic Telangiectasia = HHT) often causes severe epistaxis, of which management is a perplexing problem. This report describes our management of five cases of severe epistaxis caused by HHT. Thepatients were : a 63-year-old male who had previously undergone numerous cauterizations, a 42-year-old female who experienced shock by severe epistaxis, a 67-year-old male who had first presented cerebeller abscess, a 34-year-old female who had previously undergone septal dermoplasty, and a 73-year-old male. They were all diagnosed as having HHT. They were intensively treated with tanponade, cautery, fibrin glue, or septodermoplasty. In spite of therapy, the frequency and severity of bleeding did not improve for a long time. This indicates that there is no treatment which has long-lasting effect on bleeding.