Abstract
Rhabdomyosarcoma has been known as a malignant soft tissue tumor with poor prognosis. This tumor arises mainly in the head and neck region, but it is rare in Japan.
The patient was a 14-year-old male complaining of double vision. The patient had left exophthalmus. CT and MRI demonstrated a large tumor extending from the left orbit to the left ethmoid sinus, maxillary sinus, sphenoidal sinus and middle nasal meatus. The biopsy specimen taken from the left nasal cavity showed embryonal type rhabdomyosarcoma. This patient was treated with chemotherapy including vincristin, actinomycin-D, cyclophosphamide and pirarubicin (Regimen A), and then Regimen B consisting of vincristin, actinomycin-D and if osf amid was applied. After the chemotherapy, the tumor size reduced. For the treatment of patients with rhabdomyosarcoma, multidisciplinary treatment consisting of surgery, irradiation and combination chemotherapy is recommended.
We reviewed cases of rhabdomyosarcoma in the head and neck reported between 1961 and 1996 in Japan.
