A PROSPECTIVE STUDY OF RESPIRATORY PATHOGEN INFECTIOUS DISEASES IN BRONCHIAL ASTHMATIC PATIENTS INHALATED WITH BECLOMETHASONE DIPROPIONATE (BDP)

AS COMPARATIVE STUDY OF THESE FREQUENCY IN BRONCHIAL ASTHMATIC PATIENTS INHALATED WITHOUT BDP

Abstract

The aim of this clinical study for 5 years was to investigate the influence of beclomethasone dipropionate (BDP) inhalation therapy for bronchial asthmatic patients with an asthmatic attack (AA) on pathogen of respiratory infectious diseases. BAPTs (582) were divided into 2 groups by the rondamized table, group A with 294 Pts who were treated with BDP-inhalation and group B with 288 Pts treated without BDP-inhalation. We studied 412AA episodes of 294 Pts with BDP inhalation therapy and 294 AA episodes of 288 Pts without BDP inhalation therapy. There was no difference between two groups in percent FcC_1.0, percent VC, PaO₂, PaCO₂, pH, body temperature. Titer of CRP, count of WBC and excretion of sputum in group A was significantly higher than those in group B. Pathogen infection (bacterial infection involving with tuberuclosis, mold infection and viral infection) in group A was significantly observed more than in group B. These data suggest that BDP inhalation increases respiratory pathogen infectious diseases induced in BAPts with AA.