Abstract
The MDI (Metered-Dose Inhaler) of β-stimulants or steroids is useful for the treatment of bronchial ashma mostly on the aerosol therapy. However, the adverse-drug-reaction by overdose of these medicines can be serious. According to questionnaire survey on the MDI, only about 50% of patients could use MDI properly. Besides, many of these patients who used MDI as the doctor instructed, included a group of proper user, The ratio of overdose on only β -stimulants is higher than with steroids. Our results suggest that it is important to supply pharmaceutical instruction for a proper use of MDI.