Abstract
Objective : We studied change in specific IgE antibody levels in patients with Japanese cedar pollinosis treated by immunotherapy.
Methods : Specific IgE levels (IgE levels) forCryptomeria japonica (Cry j) andChamaecyparis obtusa (Cha o) in patients with Japanese cedar pollinosis treated by immunotherapy from 1999 to 2004 were measured and the change in these was studied by age.
Results : From 2000 to 2003, we observed a large amount of cedar pollen, and IgE levels significantly elevated postseasonally for years from 2000 to 2002 and IgE levels preseasonally dominantly elevated than those postseasonally. At 2004, we observed a small amount of cedar pollen, IgE levels showed the same at 1999 before a large amount of cedar pollen exposure.
Conclusions : IgE levels were strongly affected by the amount of cedar pollen exposure, and IgE levels were elevated after a large amount of cedar pollen exposure and followed through to the next season, and IgE levels returned to basal levels after a small amount.Even if patients were treated with cedar pollen allergen specific hyposensitization, IgE levels were affected after a large amount of cedar pollen exposure.
Abbreviations :
Cry j : Cryptomeria japonica
Cha o : Chamaecyparis obtusa
IgE : immunoglobrin E
HD : house dust
