内リンパCaイオン濃度とSPについて

抄録

Calcium ions are known to maintain the mechano-sensitivity in mudpuppy lateralline organs. Actions of these ions were investigated in guinea pig's cochleae. The calcium ions applied iontophoretically into the endolymph of the scala media augmented negative summating potentials, whereas cadmium ions, EDTA and neomycin suppressed them. N₁ components of cochlear nerve action potentials tended to increase when calcium ions applied, or in some cases of magnesium, barium and strontium applications. The increase of N₁ components did not relate to the change of microphonic potentials but it was related to that of the summating potentials. Calcium may act to regulate the mechano-sensitivity also in mammalian cochlear hair cells.