The aim of this report is to show how the nerve fibers regenerate after several lesions. Six temporal bone cases with facial paralysis of traumatic, neoplastic, and inflammatory origins were studied. Some regenerated nerve fibers were observed in the cases with severed and compressed paralysis. The nerves surrounded by, tumor cells were still edematous even at 2 months after the onset of paralysis. In this circumstance, the nerve persists to be swollen after the “initial swelling stage” of the damaged nerve. No neural tubes were observed in the nerves invaded by tumor or inflammatory cells into the nerve sheath. The finding suggests that there are no possibility of regeneration in such pathologies.