シスプラチンによる末梢前庭障害について
電子顕微鏡による検討
1989 年 20 巻 1 号 p. 59-60
詳細
1989 年 20 巻 1 号 p. 59-60
Ultrastructural changes in vestibular endorgans folloing administration of CDDP (cisplatin) were investigated using guinea pigs. Various patterns of degeneration, such as swollen mitochondria, dilatation of vesicles of Golgi's apparatus, various size of vacuoles were found in the sensory epithelia. These findings were more remarkable in type I hair cells, and in the central part of the crista ampullaris.
