会議名: 第10回バイオメディカル・ファジィ・システム学会
回次: 10
開催地: 倉敷
開催日: 1997/10/16 - 1997/10/17
p. 129-132
Teeming variable surface antigens of HIVs are induced by errorprone reverse transcriptase. Misreading, double reading, jumping reading, and frame shift reading are the essential mechanisms of antigen diversities. To predict these antigens, a cDNA coding transmembrane protein was sequenced by using universal PCR primers, analyzed and dispersed onto a evolutional time axis plate (EVTAP) using Fuzzy Logic. This EVTAP told us the future pathogenic amino acid peptide antigens to be conjugated to high molecular weight human serum proteins or HIV surface proteins for vaccination. If these predicted peptide antigens would be used prior to other anti HIV agents-treatment, mutant capture vaccine as this might exterminate HIVs to minimum levels in a patient and a healthy vaccine recipient would be protected by most types of HIV infections.