生体循環系モデルHUMANを用いたマクロ・ミクロ現象の統合シミュレーション(一般講演,ライフサイエンスとソフトンピューティング)

抄録

This paper describes an integrated perspective simulation tool of a circulatory system model in physiological movement. The large circulatory system model includes principal organs and functional units in modules, where comprehensive physiological changes are simulated such as nerve reflexes, temperature regulation, acid/base balance, O_2/CO_2 balance, and exercise control. Whereas a beat-by-beat model enables to calculate pulsational blood flows to major organs, where corresponding electrical circuit problems are solved based on the numerical analytic method. The integration with different perspective physiological changes could be applicable to the evaluation of microscopic observation in blood flows under various factors in the human body.