在宅人工呼吸器を用いた酸素療法における酸素供給源と供給方法 の違いによる吸入酸素濃度の比較

抄録

Treatment with a combination of home mechanical ventilation (HMV) and home oxygen therapy (HOT) is sometimes considered for severe patients with chronic obstructive pulmonary disease (COPD). The Japanese Respiratory Therapy Society recommends supplementing the fraction of inspired oxygen (FiO₂) by increasing ventilation frequency instead of raising the FiO₂. However, conventional HOT has been reported to fall short of achieving the target FiO₂ in a hospital setting. Furthermore, previous studies have reported a decrease in FiO₂ due to leaks during mask ventilation with non-invasive positive pressure ventilation (NPPV). In this study, we attempted to explore methods for increasing FiO₂ values in home medical care using a combination of HMV and HOT beyond what previous research has achieved. We conducted a study introducing liquid oxygen in addition to the traditional oxygen concentrator, aiming to generate new insights into the combined use of HMV and HOT. This report presents our findings.