PAIN RESEARCH
Online ISSN : 2187-4697
Print ISSN : 0915-8588
ISSN-L : 0915-8588
Review Article
Musculoskeletal pain and nerve growth factor (NGF)
Kazue Mizumura, Asako Kubo
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Keywords: NGF, Osteoarthritis, Chronic low back pain, Delayed onset muscle soreness, Antibody therapy
JOURNAL FREE ACCESS

2022 Volume 37 Issue 3 Pages 123-130

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Abstract

This review introduces the roles of nerve growth factor (NGF) in musculoskeletal pain such as osteoarthritis (OA), chronic low back pain (CLBP) and delayed onset muscle soreness. Both animal and human studies are included. In addition, therapeutic perspectives of anti–NGF antibody in treatment of bone cancer pain, OA pain and CLBP was briefly introduced.

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© 2022 Japanese Association for the Study of Pain
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