抄録
The objective of the present study is to discuss the effect of ultrasound irradiation on the
transformation ability of octacalcium phosphate (OCP) to hydroxyapatite (HAp) in simulated body fluid
(SBF). OCP powders were prepared by a reaction of an aqueous suspension of dicalcium phosphate
dehydrate and calcium carbonate at 60℃ for 12h. EDS analysis indicated that HAp converted in SBF is
calcium-deficient bone-like apatite with a Ca/P ratio of 1.53. The results from SEM observation and XRD
study demonstrated that the ultrasound irradiation exerts an influence on the OCP/HAp conversion process
particularly in the initial stage of OCP dissolution and HAp nuclear generation process, and also suggested that
the transformation rate will depend probably on the ultrasound frequency. Low-intensity pulsed ultrasound
device recently used for bone healing promoting method was also applied to elucidate the effectiveness of
ultrasound irradiation.
