加速器による医療用RIの商業生産

抄録

Medical radio-isotopes (RI) are commercially produced by accelerators or nuclear reactors. For more than a half century accelerators have routinely produced medical RI used for radiopharmaceuticals in nuclear medicine. Described here is a general introduction of commercial production of medical RI with an accelerator, and recent topics about technical development of use of an accelerator for production of ⁹⁹Mo and ²²⁵Ac. Nihon Medi-Physics has started a project of ⁹⁹Mo in-house production with an electron linear accelerator since 2019. Alpha emitting nuclide, ²²⁵Ac has attracted much attention recently for therapeutic applications based on the concept of Theranostics. ²²⁵Ac supply currently relies solely on ²²⁹Th generator but alternative production method with an accelerator has been being developed.