Abstract
Bioactive calcium phosphate bone cement (CPC) has been developed for clinical use. The powder component of CPC consists of α-TCP, TeCP, DCPD, HA and a stabilizer, while the liquid is an aqueous solution containing sodium chondroitin sulfate, sodium succinate, and a stabilizer. The mixture can set within about 10 minutes after mixing in a physiological condition. The mixture also sets in the simulated body fluid (SBF) without severe change in pH and gradually turns into low crystalline carbonated hydroxyapatite. Compressive strength of the hardened body reaches its final strength more than 80MPa in 3 days soaked in SBF at 37°C.