Apatite deposition on self-assembled monolayer induced by Spatial Design

Abstract

We prepared self-assembled monolayers(SAM) of alkanethiols having CH₃, COOH, OH and NH₂ terminal groups on sputter-coated Au films on mirror polished SUS316L. We fabricated such special set-up(spatial design) as these SAM specimens, where a SAM surface was faced to another one with intervals of 0.1-1.0 mm. Then, they were soaked in a simulated body fluid(Kokubo solution,SBF,pH7.4,36.5C)in order to evaluate their apatite formation(in vitro bioactivity). It is concluded that apatite deposition on SAMs in the spatial design depended on the surface charge of the SAMs.