Effects of autoclaving on spatial design-induced apatite-forming ability

Abstract

Titania layers were prepared by thermal oxidation of titanium substrates (HT) at various temperature, then they were autoclaved (HTa). We fabricated special set-up (spatial design) of these specimens, where the titania layer surface was faced to another one with intervals of 0.3 mm. Then, they were soaked in a simulated body fluid (SBF) for 7 days. Apatite deposited on HT and HTa hear-treated at 350 or 400°C. HT heat-treated at 300°C did not deposit apatite particles without autoclaving. These results indicated that autoclaving is effective for enhancement of in vitro apatite-forming ability of titania layer.