Preprints of Annual Meeting of The Ceramic Society of Japan
Preprints of Fall Meeting of The Ceramic Society of Japan
Annual Meeting of The Ceramic Society of Japan, 2012
Session ID : 1P095
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Preparation of mesoporous zirconia for improvement of thermal stability of immobilized enzyme.
*yuichi masuda, katsuya kato, akari hayashi
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Keywords: mesoporous zirconia, thermal stability
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Abstract
Formaldehyde dehydrogenase (FDH) immobilized on mesoporous silica (MPS) could not improve the thermal stability. In present study, we prepared the FDH immobilized on mesoporous zirconia (MPZ) for improvement of thermal stability. As a result, FDH immobilized on MPZ showed higher thermal stability and substrate affinity than that on MPS. The reason was considered to be highly biocompatible and mesoporous structure of MPZ. This material is applicable to DDS carriers for heat-sensitive drug and biomolecules.
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© The Ceramic Society of Japan 2012
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