2024 Volume 104 Issue 1 Pages 117-119
A 66-year-old man was diagnosed with T-cell large granular lymphocytic leukemia two years before he visited our hospital and had been receiving cyclophosphamide. Six months earlier, he had abdominal discomfort, diarrhea, and pancytopenia. He was referred to our hospital because PET-CT showed abnormal accumulations in the large intestine. Colonoscopy revealed irregular ulcers and stenosis in the rectum and sigmoid colon, and it was diagnosed as monomorphic epitheliotropic intestinal T-cell lymphoma in pathological examination. MEITL is an extremely rare primary malignant tumor of the gastrointestinal tract and the standard treatment regimens are not established. In our case, he was treated with CHOP and SMILE (dexamethasone, methotrexate, ifosfamide, L-asparaginase, etoposide) and it was effective for the colonic stenosis and ulcer.
