A case of gastrointestinal amyloidosis diagnosed by characteristic endoscopic findings and computed tomography

Abstract

A 90-year-old man was referred to our hospital for researching anemia and duodenal tumor. Computed tomography showed circumferential wall thickening from duodenal descending part to jejunum. Upper gastrointestinal endoscopy revealed multiple submucosal tumor-like protrusions attached fresh blood from duodenal descending part to duodenal horizontal part. A duodenal biopsy revealed amyloid deposition in the lamina propria mucosa. These findings were consistent with amyloidosis. Additionally, there were no underlying disease and other organ failure. Considering characteristic endoscopic findings, we diagnosed this patient as primary AL amyloidosis. Symptoms with anemia improved by transfusion and iron supplement. Gastrointestinal amyloidosis is a rare disease. It is very important to remember gastrointestinal amyloidosis from characteristic endoscopic findings and computed tomography. In that case, you had better perform the biopsy from the characteristic lesion.