A man in 50s with a history of Helicobacter pylori eradication therapy was taking loxoprofen daily without a proton pump inhibitor and was admitted to the hospital with abdominal pain and tarry stools. Esophagogastroduodenoscopy revealed duodenal ulcer scars, a shallow ulcer in the postbulbar duodenum, and a strictured superior duodenal angulus, which was impassable with the scope. Because other conditions such as intestinal tuberculosis and Crohn's disease were ruled out, the stricture was presumed to have resulted from repeated ulcer remissions and flare-ups due to nonsteroidal anti-inflammatory drug use. After initiation of proton pump inhibitor therapy, endoscopic balloon dilation was performed on the stricture. The patient was subsequently able to resume eating. No stricture was observed on esophagogastroduodenoscopy 3 months after endoscopic balloon dilation, indicating its effectiveness for benign duodenal stenosis.
