MALT lymphoma of the stomach which was very well indicated to the erdication therapy against Helicobacter pylori. Report of a Case

Abstract

A 70yeas-old male visited us with a suspect diagnosis of MALT lymphoma following the x-ray mass screening of the stomach done in Nov. 1999. Through endscope of upper gastro-intestinal tract, multiple irregular-spaced ulcers and adjacent reddened alterations which were grainy and smooth-surfaced were discerned in the wide-spaced area from the angle to the posterior wall of the pyloric antrum. The biopsy specimen involved led to the diagnosis of MALT lymphoma since lympho-epithelial lesion (LEL) and proliferation of small-sized lymphocytes accompany cleaved cells were present. Furthermore, genereconstruction in heavy chain was admitted to support the previous view.
Since H. pylori was positive, the eradication therapy followed.
One month after the therapy started, multiple ulcers decreased in number and size. More two months thereafter, multiple ulcers had thoroughly disappeared.
Nine months in all after the beginning of the therapy, findings in the pyloric antrum had cpmpletely altered into the atrophic pattern of the mucous membrane showing whitish hue, surprisingly improved.
The patient is now being under observation with no excerbation during the disease course.