2001 Volume 59 Issue 2 Pages 64-65
A case of fibrolipomatous submucosal tumor of esophagus was reported. A 59-year-old male complained of dysphagia and he was pointed out esophageal tumor at medical checkup. Upper GI study showed a elevated lesion at middle and lower esophagus, in size 10×3 cm. Endoscopic examination showed a smooth submucosal tumor and EUS reveraled it's hypoechoic, isogenic tumor in 3rd layer. We diagnosed the benign submucosal tumor, but there were symptom and possibility of malignancy, so operation was performed. Histologically, the tumor, which was consisted of spindle cell and large amount of fibrous tissue, was diagnosed as GIST. It also was conteined many fat cells, which resembled fibrolipoma. Immunohistochemical staining indicated S-100 negative, α-SMA negative, CD34 positive and c-kit negative. However the tumor was classfied as uncommited type of GIST according to Rosai's classification, histology and the result of Immunohistochemical examination was atypical.
