抄録
We descride a 63-year-old man, who turned out to be positive for fecal occult blood test on November, 2001. Colonoscopy was carried out on May 2002, and there were multiple polypoid lesions predominantly in proximal colon. On February 2003, Endscopic mucosal resection (EMR) of Isp'polyp (12mm in size) , LST (granular type ; 16mm in size) both located in ascending colon was perforemed. Pathological findings revealed carcinoma in adenoma in both resions. In recent years, attenuated familial adenomatous polyposis (AFAP) attract a great deal of attention. The mutations in APC and MYH gene are reported to be associated with AFAP. We analyzed mutation of APC and MYH gene. In this case, no mutation of both gene was detected. We report a rare case of colon poilyposis resembling AFAP.
