H．pylori eradication therapy of MALT Lymphoma and Follicular Lymphoma of duodenum

Abstract

Malignant Lymphoma occures most commonly in the stomach, thereas in the small intestine, especially in the duodenum, are very rare. So, little is known about clinicopatologic characteristics and treatment of duodenal MALT and follicular lymphoma.
Form January 1998 to July 2003, we experienced 11 duodenal lymphoma (5 MALT lymphoma, 6 follicular lymphoma were treated by eradication therapy for H. pylori. Complete remission (CR) was found in one case, and partial remission (PR) was found in 2 cases. On the other hand, we perfomed H. pylori eradication therapy in 2 patients of duodenal follicular lymphoma, but none of them got response.
We suggest the H. pylori eradication therapy may be considerad the first choice for duodenal MALT lymphoma because of its low risk. On the other hand, for duodenal follicular lymphoma, H. pylori eradication therapy is not effective.